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Characterisation and Design of Tissue Scaffolds

2015-10-30 Technology & Engineering
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Release : 2015-10-30
Genre : Technology & Engineering
Kind : eBook
Book Rating : 959/5 ( reviews)

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Book Synopsis Characterisation and Design of Tissue Scaffolds by : Paul Tomlins

Download or read book Characterisation and Design of Tissue Scaffolds written by Paul Tomlins. This book was released on 2015-10-30. Available in PDF, EPUB and Kindle. Book excerpt: Characterisation and Design of Tissue Scaffolds offers scientists a useful guide on the characterization of tissue scaffolds, detailing what needs to be measured and why, how such measurements can be made, and addressing industrially important issues. Part one provides readers with information on the fundamental considerations in the characterization of tissue scaffolds, while other sections detail how to prepare tissue scaffolds, discuss techniques in characterization, and present practical considerations for manufacturers. Summarizes concepts and current practice in the characterization and design of tissue scaffolds Discusses design and preparation of scaffolds Details how to prepare tissue scaffolds, discusses techniques in characterization, and presents practical considerations for manufacturers

Characterization of Biomaterials

2013-03-12 Science
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Release : 2013-03-12
Genre : Science
Kind : eBook
Book Rating : 028/5 ( reviews)

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Book Synopsis Characterization of Biomaterials by : Julia Will

Download or read book Characterization of Biomaterials written by Julia Will. This book was released on 2013-03-12. Available in PDF, EPUB and Kindle. Book excerpt: In order to enhance the application potential of scaffolds in tissue engineering, comprehensive characterization of scaffold micro- and macro-structure, porosity, permeability and mechanical properties are required. In addition, before in vivo studies can be carried out, a complete assessment of the in vitro behavior of scaffolds, e.g. in selected cell culture studies, is required. The present chapter revises the wide range of methods applied to characterize scaffolds and emphasizes the need for a combination of different characterization techniques for understanding scaffold performance required for successful bone regeneration.

Development and Characterisation of Completely Degradable Composite Tissue Engineering Scaffolds

2007
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Release : 2007
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Book Synopsis Development and Characterisation of Completely Degradable Composite Tissue Engineering Scaffolds by :

Download or read book Development and Characterisation of Completely Degradable Composite Tissue Engineering Scaffolds written by . This book was released on 2007. Available in PDF, EPUB and Kindle. Book excerpt: ABSTRACT The field of Tissue Engineering has developed in response to the shortcomings associated to the replacement of tissues lost to disease or trauma: donor tissue rejection, chronic inflammation, and donor tissue shortages. The driving force behind Tissue Engineering is to avoid these problems by creating biological substitutes capable of replacing the damaged tissue. This is done by combining scaffolds, cells and signals in order to create living, physiological, three-dimensional tissues. Scaffolds are porous biodegradable structures that are meant to be colonised by cells and degrade in time with tissue generation. Scaffold design and development is mainly an engineering challenge, and is the goal of this PhD thesis. The main aim of this thesis is to develop and characterise scaffolds for Tissue Engineering applications. Specifically, its objectives are: 1. To study, optimise and characterise two scaffold processing methods: Solvent Casting and Phase Separation. This is done by experiment design analysis. 2. To characterise the degradation, surface properties, and cellular behaviour of the scaffolds produced. The scaffolds are made of a composite of polylactic acid polymer and a calcium phosphate soluble glass. The comparison of the two processing methods reveals that in general, the solvent cast scaffolds have higher porosities and lower mechanical properties than the phase-separated ones. Two compositions containing 20 weight % and 50 weight % of glass particles were chosen for further characterisations including degradation, surface properties and cellular behaviour. The degradation of the scaffolds was studied for a period of 10 weeks. The evolution of various parameters such as: morphology, weight loss, mechanical properties, thermal transitions and porosity, was monitored. Scaffolds produced via solvent casting were found to be more severely affected by degradation than phase-separated ones. The surface properties of the scaffolds were measured by model.

The Design, Manufacture and Characterisation of Polycaprolactone Scaffolds and a Novel Modular Perfusion Bioreactor Strategy for Bone Tissue Engineering

2011 Bone regeneration
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Release : 2011
Genre : Bone regeneration
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Book Synopsis The Design, Manufacture and Characterisation of Polycaprolactone Scaffolds and a Novel Modular Perfusion Bioreactor Strategy for Bone Tissue Engineering by : Peter John Christopher Felstead

Download or read book The Design, Manufacture and Characterisation of Polycaprolactone Scaffolds and a Novel Modular Perfusion Bioreactor Strategy for Bone Tissue Engineering written by Peter John Christopher Felstead. This book was released on 2011. Available in PDF, EPUB and Kindle. Book excerpt:

Design, Fabrication and Characterization of Biodegradable Scaffolds for Tissue Engineering and Regenerative Medicine Applications

2018 Biodegradation
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Release : 2018
Genre : Biodegradation
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Book Synopsis Design, Fabrication and Characterization of Biodegradable Scaffolds for Tissue Engineering and Regenerative Medicine Applications by : Muhammad Anwaar Nazeer

Download or read book Design, Fabrication and Characterization of Biodegradable Scaffolds for Tissue Engineering and Regenerative Medicine Applications written by Muhammad Anwaar Nazeer. This book was released on 2018. Available in PDF, EPUB and Kindle. Book excerpt:

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