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Cellular Signal Transduction in Toxicology and Pharmacology

2019-04-16 Science
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Release : 2019-04-16
Genre : Science
Kind : eBook
Book Rating : 265/5 ( reviews)

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Book Synopsis Cellular Signal Transduction in Toxicology and Pharmacology by : Jonathan W. Boyd

Download or read book Cellular Signal Transduction in Toxicology and Pharmacology written by Jonathan W. Boyd. This book was released on 2019-04-16. Available in PDF, EPUB and Kindle. Book excerpt: Covering a key topic due to growing research into the role of signaling mechanisms in toxicology, this book focuses on practical approaches for informatics, big data, and complex data sets. Combines fundamentals / basics with experimental applications that can help those involved in preclinical drug studies and translational research Includes detailed presentations of study methodology and data collection, analysis, and interpretation Discusses tools like experimental design, sample handling, analytical measurement techniques

Signaling and the Cytoskeleton

2013-03-09 Science
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Release : 2013-03-09
Genre : Science
Kind : eBook
Book Rating : 930/5 ( reviews)

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Book Synopsis Signaling and the Cytoskeleton by : Kermit L. Carraway

Download or read book Signaling and the Cytoskeleton written by Kermit L. Carraway. This book was released on 2013-03-09. Available in PDF, EPUB and Kindle. Book excerpt: This monograph explores the relationships between cell signaling and the cytoplasmic cytoskeleton in fundamental cell processes, thus bridging the gap between two very active aspects of molecular cell biology. It covers the two main - and reciprocal - questions of these relationships: How are structure and function of the cytoskeleton affected by external signals which impinge on the cell? How does the cytoskeleton influence the cellular signaling processes which determine cell behavior?

Toxins and Signal Transduction

1997-05-22 Science
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Release : 1997-05-22
Genre : Science
Kind : eBook
Book Rating : 780/5 ( reviews)

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Book Synopsis Toxins and Signal Transduction by : Yehuda Gutman

Download or read book Toxins and Signal Transduction written by Yehuda Gutman. This book was released on 1997-05-22. Available in PDF, EPUB and Kindle. Book excerpt: Of the multitude of toxins known and the enormous variety of effects they cause, of particular interest are those that influence signal transduction. Intercellular communication by chemical signals is essential for the functioning of multicellular organisms. Many toxins exert their biological effects by interfering with the signal transduction initiated by these chemicals (hormones, transmitters, growth factors, and other mediators). Up-to-date information is provided by outstanding experts, who discuss the molecular mechanisms involved in the action of many toxins, as well as the use of toxins as informative tools with which to study signal transduction and their potential therapeutic usage. This volume contains useful information for the experimentalist interested in toxins or in signal transduction, as well as for the reader interested in gaining a comprehensive overview of the field. The Cellular and Molecular Mechanisms of Toxin Action series will include monographs on signal transduction, secretory systems, cytoskeleton, selective neurotoxicity of natural, recombinant and chimeric toxins giving a broader emphasis on the mechanism of action, structure-function relationship, and use of toxins as research tools and their therapeutic applications.

Signal Transduction

2015-10-23 Science
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Release : 2015-10-23
Genre : Science
Kind : eBook
Book Rating : 193/5 ( reviews)

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Book Synopsis Signal Transduction by : ljsbrand M. Kramer

Download or read book Signal Transduction written by ljsbrand M. Kramer. This book was released on 2015-10-23. Available in PDF, EPUB and Kindle. Book excerpt: A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor – ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition. - In-depth insight into a subject central to cell biology and fundamental to biomedicine, including the search for novel therapeutic interventions - Essential signaling events embedded in rich physiological and pathological contexts - Extensive conceptual colour artwork to assist with comprehension of key topics - Special emphasis on how molecular structure determines protein function and subcellular localization - Employment of unambiguous protein names (symbols) in agreement with leading protein- and gene databases, allowing the learner to extend his/her exploration on the web

Oxidative Stress and Signal Transduction

2012-12-06 Science
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Release : 2012-12-06
Genre : Science
Kind : eBook
Book Rating : 812/5 ( reviews)

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Book Synopsis Oxidative Stress and Signal Transduction by : H.J. Forman

Download or read book Oxidative Stress and Signal Transduction written by H.J. Forman. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: In the past few years there has been the increased recognition that the effects of oxidative stress are not limited to the damage of cellular constituents. There is now evidence that reactive oxygen species (ROS) can alter cell function by acting upon the intermediates, or second messengers, in signal transductions. Such effects on signaling mechanisms probably account for the role of oxidative stress in inflammation, aging, and cancer. This volume brings together internationally recognized researchers in both the major areas covered by the book, oxidative stress and signal transduction. The work is organized in three sections. The first deals with the immediate cellular responses to oxidative stress and the production of second messengers. The second details the connection between second messengers and the gene. The third part looks more closely at the level of the gene.

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