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Epigenetics in Precision Medicine

2021-11-12 Medical
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Release : 2021-11-12
Genre : Medical
Kind : eBook
Book Rating : 058/5 ( reviews)

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Book Synopsis Epigenetics in Precision Medicine by : Jose Luis Garcia-Gimenez

Download or read book Epigenetics in Precision Medicine written by Jose Luis Garcia-Gimenez. This book was released on 2021-11-12. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, knowledge of epigenetic mechanisms underlying disease onset and progression has proven crucial for the development of novel early diagnosis and prognosis biomarkers for patient stratification and precision medicine. Epigenetics in Precision Medicine, a new volume in the Translational Epigenetics series, provides a thorough discussion and overview of current developments in clinical epigenetics with special emphasis on epigenetic biomarkers that can be used for clinical diagnosis, prognosis, patient stratification, and treatment monitoring. Disease types discussed include cancer, metabolic disorders, neurodegenerative diseases, bone disease, and immune-related disorders. The book examines the challenges of advancing epigenetics research and translating findings to the clinic and drug discovery in each of these areas, as well as current solutions; chapter authors discuss how to leverage epigenomic technologies, applications, and tools, such as next-generation sequencing, to discover new epigenetic biomarkers in disease and drug studies. Epigenetics in Precision Medicine focuses on complex epigenetic mechanisms in several pathologies, and explores how epigenetics can power the advance of precision medicine, not only by improving in vitro diagnostic and prognostic tools, but by providing new therapeutic approaches to treat human disease. Provides a thorough grounding in epigenetics-driven precision medicine, with emphasis on developing and implementing early diagnosis and prognosis biomarkers, and supporting patient stratification Empowers researchers and clinicians to incorporate epigenetics in new disease research, drug discovery, and clinical practice Features chapter contributions from international leaders in the field

Cancer Epigenetics for Precision Medicine

2018-10-12 Medical
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Release : 2018-10-12
Genre : Medical
Kind : eBook
Book Rating : 504/5 ( reviews)

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Book Synopsis Cancer Epigenetics for Precision Medicine by : Ramona G. Dumitrescu

Download or read book Cancer Epigenetics for Precision Medicine written by Ramona G. Dumitrescu. This book was released on 2018-10-12. Available in PDF, EPUB and Kindle. Book excerpt: This volume discusses certain epigenetic changes recognized in early carcinogenic lesions and different tumors, as well as factors that alter the epigenome and epigenetic profile such as diet, alcohol, immunity, circadian rhythm, and more. The chapters in this book further delve into this field and cover topics such as epigenome-based precision medicine in lung cancer; interplay between genetic and epigenetic changes in breast cancer subtypes; genetic regulation of PDCD1 gene in cancer immunology; and pyrosequencing methylation analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Cancer Epigenetics for Precision Medicine: Methods and Protocols is a valuable resource to help researchers and scientists identify these specific biomarkers and work towards the prevention, diagnosis, and prognosis of different cancers in the future.

Cancer Epigenetics for Precision Medicine

2019-09-17 Medical
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Release : 2019-09-17
Genre : Medical
Kind : eBook
Book Rating : 833/5 ( reviews)

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Book Synopsis Cancer Epigenetics for Precision Medicine by : Ramona G. Dumitrescu

Download or read book Cancer Epigenetics for Precision Medicine written by Ramona G. Dumitrescu. This book was released on 2019-09-17. Available in PDF, EPUB and Kindle. Book excerpt: This volume discusses certain epigenetic changes recognized in early carcinogenic lesions and different tumors, as well as factors that alter the epigenome and epigenetic profile such as diet, alcohol, immunity, circadian rhythm, and more. The chapters in this book further delve into this field and cover topics such as epigenome-based precision medicine in lung cancer; interplay between genetic and epigenetic changes in breast cancer subtypes; genetic regulation of PDCD1 gene in cancer immunology; and pyrosequencing methylation analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Cancer Epigenetics for Precision Medicine: Methods and Protocols is a valuable resource to help researchers and scientists identify these specific biomarkers and work towards the prevention, diagnosis, and prognosis of different cancers in the future.

Epigenetic Biomarker and Personalized Precision Medicine

2020-12-21 Science
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Release : 2020-12-21
Genre : Science
Kind : eBook
Book Rating : 849/5 ( reviews)

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Book Synopsis Epigenetic Biomarker and Personalized Precision Medicine by : Jiucun Wang

Download or read book Epigenetic Biomarker and Personalized Precision Medicine written by Jiucun Wang. This book was released on 2020-12-21. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Clinical Precision Medicine

2019-11-15 Medical
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Release : 2019-11-15
Genre : Medical
Kind : eBook
Book Rating : 028/5 ( reviews)

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Book Synopsis Clinical Precision Medicine by : Judy S. Crabtree

Download or read book Clinical Precision Medicine written by Judy S. Crabtree. This book was released on 2019-11-15. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Precision Medicine: A Primer offers clinicians, researchers and students a practical, up-to-date resource on precision medicine, its evolving technologies, and pathways towards clinical implementation. Early chapters address the fundamentals of molecular biology and gene regulation as they relate to precision medicine, as well as the foundations of heredity and epigenetics. Oncology, an early adopter of precision approaches, is considered with its relationship to genetic variation in drug metabolism, along with tumor immunology and the impact of DNA variation in clinical care. Contributions by Stephanie Kramer, a Clinical Genetic Counselor, also provide current information on prenatal diagnostics and adult genetics that highlight the critical role of genetic counselors in the era of precision medicine. Includes applied discussions of chromosomes and chromosomal abnormalities, molecular genetics, epigenetic regulation, heredity, clinical genetics, pharmacogenomics and immunogenomics Features chapter contributions from leaders in the field Consolidates fundamental concepts and current practices of precision medicine in one convenient resource

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