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Bioinformatics for Diagnosis, Prognosis and Treatment of Complex Diseases

2013-11-25 Science
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Release : 2013-11-25
Genre : Science
Kind : eBook
Book Rating : 755/5 ( reviews)

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Book Synopsis Bioinformatics for Diagnosis, Prognosis and Treatment of Complex Diseases by : Bairong Shen

Download or read book Bioinformatics for Diagnosis, Prognosis and Treatment of Complex Diseases written by Bairong Shen. This book was released on 2013-11-25. Available in PDF, EPUB and Kindle. Book excerpt: The book introduces the bioinformatics tools, databases and strategies for the translational research, focuses on the biomarker discovery based on integrative data analysis and systems biological network reconstruction. With the coming of personal genomics era, the biomedical data will be accumulated fast and then it will become reality for the personalized and accurate diagnosis, prognosis and treatment of complex diseases. The book covers both state of the art of bioinformatics methodologies and the examples for the identification of simple or network biomarkers. In addition, bioinformatics software tools and scripts are provided to the practical application in the study of complex diseases. The present state, the future challenges and perspectives were discussed. The book is written for biologists, biomedical informatics scientists and clinicians, etc. Dr. Bairong Shen is Professor and Director of Center for Systems Biology, Soochow University; he is also Director of Taicang Center for Translational Bioinformatics.

Essentials of Bioinformatics, Volume II

2019-10-18 Science
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Release : 2019-10-18
Genre : Science
Kind : eBook
Book Rating : 750/5 ( reviews)

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Book Synopsis Essentials of Bioinformatics, Volume II by : Noor Ahmad Shaik

Download or read book Essentials of Bioinformatics, Volume II written by Noor Ahmad Shaik. This book was released on 2019-10-18. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics is an integrative field of computer science, genetics, genomics, proteomics, and statistics, which has undoubtedly revolutionized the study of biology and medicine in past decades. It mainly assists in modeling, predicting and interpreting large multidimensional biological data by utilizing advanced computational methods. Despite its enormous potential, bioinformatics is not widely integrated into the academic curriculum as most life science students and researchers are still not equipped with the necessary knowledge to take advantage of this powerful tool. Hence, the primary purpose of our book is to supplement this unmet need by providing an easily accessible platform for students and researchers starting their career in life sciences. This book aims to avoid sophisticated computational algorithms and programming. Instead, it focuses on simple DIY analysis and interpretation of biological data with personal computers. Our belief is that once the beginners acquire these basic skillsets, they will be able to handle most of the bioinformatics tools for their research work and to better understand their experimental outcomes. Our second title of this volume set In Silico Life Sciences: Medicine provides hands-on experience in analyzing high throughput molecular data for the diagnosis, prognosis, and treatment of monogenic or polygenic human diseases. The key concepts in this volume include risk factor assessment, genetic tests and result interpretation, personalized medicine, and drug discovery. This volume is expected to train readers in both single and multi-dimensional biological analysis using open data sets, and provides a unique learning experience through clinical scenarios and case studies.

Cancer Genomics

2013-02-12 Medical
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Release : 2013-02-12
Genre : Medical
Kind : eBook
Book Rating : 421/5 ( reviews)

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Book Synopsis Cancer Genomics by : Ulrich Pfeffer

Download or read book Cancer Genomics written by Ulrich Pfeffer. This book was released on 2013-02-12. Available in PDF, EPUB and Kindle. Book excerpt: The combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics and mutations with its propensity to metastasize and to respond to therapy. It is not just one or a few genes, it is the complex alteration of the genome that determines cancer development and progression. Future management of cancer patients will therefore rely on thorough molecular analyses of each single case. Through this book, students, researchers and oncologists will obtain a comprehensive picture of what the first ten years of cancer genomics have revealed. Experts in the field describe, cancer by cancer, the progress made and its implications for diagnosis, prognosis and treatment of cancer. The deep impact on the clinics and the challenge for future translational research become evident.

Pulmonomics: Omics Approaches for Understanding Pulmonary Diseases

2023-11-18 Medical
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Release : 2023-11-18
Genre : Medical
Kind : eBook
Book Rating : 048/5 ( reviews)

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Book Synopsis Pulmonomics: Omics Approaches for Understanding Pulmonary Diseases by : Sudipto Saha

Download or read book Pulmonomics: Omics Approaches for Understanding Pulmonary Diseases written by Sudipto Saha. This book was released on 2023-11-18. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively reviews various omics approaches like genomics, proteomics, transcriptomics, and metabolomics for understanding pulmonary disease at molecular and systems levels. The initial chapters present the pathogenesis of major pulmonary diseases, namely, obstructive diseases, restrictive diseases, vascular diseases, infectious diseases, and neoplastic carcinoma. The book chapters provide current information about the role of the microbiome and applications of medical imaging, bioinformatics tools, and databases for diagnosis and designing treatment strategies against complex lung diseases. Further, the book discusses omics technologies to identify biomarkers for the early diagnosis and prognosis of pulmonary diseases. Finally, the book elucidates the multi-omics approaches and data integration using mathematical modeling for insights into the disease etiology towards improving the prognostics and predictive accuracy of disease phenotypes. ​

Bioinformatics Approaches to Biomarker and Drug Discovery in Aging and Disease

2012
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Release : 2012
Genre :
Kind : eBook
Book Rating : 609/5 ( reviews)

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Book Synopsis Bioinformatics Approaches to Biomarker and Drug Discovery in Aging and Disease by : Kristen Fortney

Download or read book Bioinformatics Approaches to Biomarker and Drug Discovery in Aging and Disease written by Kristen Fortney. This book was released on 2012. Available in PDF, EPUB and Kindle. Book excerpt:

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