Bioassays in Experimental and Preclinical Pharmacology

2021 Biological assay

Author : Karuppusamy Arunachalam
Release : 2021
Genre : Biological assay
Kind : eBook
Book Rating : 330/5 ( reviews)

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Book Synopsis Bioassays in Experimental and Preclinical Pharmacology by : Karuppusamy Arunachalam

Download or read book Bioassays in Experimental and Preclinical Pharmacology written by Karuppusamy Arunachalam. This book was released on 2021. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book explores protocols for a wide array of preclinical pharmacology and toxicology evaluations to be applied to chemical drugs and their development through in vitro, involving tissues and cell lines, and in vivo models, using animals as experimental systems, utilized to conduct pharmacological research. Written for the Springer Protocols Handbooks series, the methodologies included in this collection have been standardized by the authors through extensive use in the lab so that they are ready to be applied in the labs of readers around the world. Authoritative and practical, Bioassays in Experimental and Preclinical Pharmacology aims to assist undergraduate and postgraduate students, research scholars, scientists, and other academicians performing research in the vital field of drug discovery.

Bioassay Methods in Natural Product Research and Drug Development

1999-01-31 Medical

Author : Lars Bohlin
Release : 1999-01-31
Genre : Medical
Kind : eBook
Book Rating : 802/5 ( reviews)

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Book Synopsis Bioassay Methods in Natural Product Research and Drug Development by : Lars Bohlin

Download or read book Bioassay Methods in Natural Product Research and Drug Development written by Lars Bohlin. This book was released on 1999-01-31. Available in PDF, EPUB and Kindle. Book excerpt: Bioassay Methods in Natural Product Research and Drug Development contains the proceedings from the Phytochemical Society of Europe's very successful symposium on this topic, held August 24-27, 1997 in Uppsala, Sweden. In this volume, leading academic and industrial scientists discuss novel methods for assaying natural products to find new structure-activity relationships. Of key importance in this process is the availability and reliability of specific bioassay methods, but chapters also discuss chemical and biological diversity and how to dereplicate natural product extracts to increase efficiency in lead discovery. Anti-tumor, HIV-inhibitory, antiprotozoal, anti-infective and immunomodulatory natural products are discussed. Various industrial projects are presented for the first time. This volume bridges the gap between academic and industrial research and scientists, and should be required reading in drug companies and faculties of pharmacy, as well as serving scientists in pharmacognosy, pharmacology, phytochemistry, natural products and drug discovery.

Pharmaceutical Bioassays

2009-11-09 Medical

Author : Shiqi Peng
Release : 2009-11-09
Genre : Medical
Kind : eBook
Book Rating : 605/5 ( reviews)

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Book Synopsis Pharmaceutical Bioassays by : Shiqi Peng

Download or read book Pharmaceutical Bioassays written by Shiqi Peng. This book was released on 2009-11-09. Available in PDF, EPUB and Kindle. Book excerpt: The definitive compendium of bioassay procedures and applications A virtual encyclopedia of key bioassay protocols, this up-to-date, essential resource reviews the methods and applications of bioassays that quantify drug activity and evaluate the validity of pharmacological models. Demonstrating the specific ways in which various pharmaceutical bioassays interpret the activity of drug molecules, the book covers the evaluation and screening of drug compounds in a wide spectrum of therapeutic categories. Throughout, the authors use various models to link experimental observations with findings that clarify the effect of drug compounds on cellular biology and measure the pharmacological activity of chemical substances. This provides an important technological platform for successful drug research and clinical therapy, making Pharmaceutical Bioassays an ideal sourcebook for pharmacologists, pharmaceutical and medical researchers, analytical chemists, toxicologists, and students. Just as a fundamental knowledge of pharmaceutical bioassays is vital to understanding how bioactive agents and new drugs are defined, discovered, and developed, so too is this indispensable reference, which: Offers a complete reference on pharmaceutical bioassays and their specific applications in the assessment of therapies for cancer, Alzheimer’s, diabetes, epilepsy, inflammation, antimalarials, pharmacogenomics, and other major therapeutic areas Covers bioassays that measure toxicity, including those for chemical toxicity and hepatoxicity—a particularly significant consideration in the development of safe and tolerable medications Highlights clinically relevant methods, ideas, and techniques to support any pharmaceutical researcher Suggests guidelines and systems to enhance communication between pharmacologists, chemists, and biologists Provides an informative analysis of pharmaceutical bioassay technologies and lab applications

In Vitro Experimental Pharmacology

2019-04-30 Medical

Author : Asmita Gajbhiye Patil
Release : 2019-04-30
Genre : Medical
Kind : eBook
Book Rating : 938/5 ( reviews)

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Book Synopsis In Vitro Experimental Pharmacology by : Asmita Gajbhiye Patil

Download or read book In Vitro Experimental Pharmacology written by Asmita Gajbhiye Patil. This book was released on 2019-04-30. Available in PDF, EPUB and Kindle. Book excerpt: In the context of drug discovery and development, in vivo experimentation should be performed only if is necessary and well-conceived. From both an ethical and practical perspective, in vitro bioassays are more viable and efficacious in the preliminary pharmacological screening of a newly-discovered drug molecule. This book will be of immense value to both the experienced as well as new researchers in biomedicine. It discusses anti-inflammatory, antioxidant, antidiabetic, antimicrobial, antimalarial, antileshmanial and anticancer bioassays. Additionally the book discusses the basic concepts governing experimental pharmacology and a chapter dealing with enzyme-based bioassays has also been incorporated. The assays described in the book include step-by-step experimental procedures preceded with an explanation of the principal and theory governing the procedure.

Bioassay Techniques for Drug Development

2001-10-04 Medical

Author : Atta-ur-Rahman
Release : 2001-10-04
Genre : Medical
Kind : eBook
Book Rating : 228/5 ( reviews)

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Book Synopsis Bioassay Techniques for Drug Development by : Atta-ur-Rahman

Download or read book Bioassay Techniques for Drug Development written by Atta-ur-Rahman. This book was released on 2001-10-04. Available in PDF, EPUB and Kindle. Book excerpt: The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassa

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Bioassays in Experimental and Preclinical Pharmacology

Bioassay Methods in Natural Product Research and Drug Development

Pharmaceutical Bioassays

In Vitro Experimental Pharmacology

Bioassay Techniques for Drug Development

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