1# Library to Find Best eBook for Read
Author : Eswar Shankar
Release : 2023-05-25
Genre : Science
Kind : eBook
Book Rating : 060/5 ( reviews)
Book Synopsis Adapting drug repurposing to overturn drug resistance in cancer by : Eswar Shankar
Download or read book Adapting drug repurposing to overturn drug resistance in cancer written by Eswar Shankar. This book was released on 2023-05-25. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kenneth K.W. To
Release : 2020-07-29
Genre : Science
Kind : eBook
Book Rating : 032/5 ( reviews)
Book Synopsis Drug Repurposing in Cancer Therapy by : Kenneth K.W. To
Download or read book Drug Repurposing in Cancer Therapy written by Kenneth K.W. To. This book was released on 2020-07-29. Available in PDF, EPUB and Kindle. Book excerpt: Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource. Presents a systematic and up-to-date collection of the research underpinning the various drug repurposing approaches for a quick, but in-depth understanding on current trends in drug repurposing research Brings better understanding of the drug repurposing process in a holistic way, combining both basic and clinical sciences Encompasses a collection of successful stories of drug repurposing for cancer therapy in different cancer types
Author : Institute of Medicine
Release : 2014-02-06
Genre : Medical
Kind : eBook
Book Rating : 492/5 ( reviews)
Book Synopsis Improving and Accelerating Therapeutic Development for Nervous System Disorders by : Institute of Medicine
Download or read book Improving and Accelerating Therapeutic Development for Nervous System Disorders written by Institute of Medicine. This book was released on 2014-02-06. Available in PDF, EPUB and Kindle. Book excerpt: Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.
Author : Anne Le
Release : 2018-06-26
Genre : Medical
Kind : eBook
Book Rating : 36X/5 ( reviews)
Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le
Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le. This book was released on 2018-06-26. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Author : Natesan Ramalingam Iyer
Release : 2020-06-27
Genre : Social Science
Kind : eBook
Book Rating : 042/5 ( reviews)
Book Synopsis A PATH TO DISCOVER by : Natesan Ramalingam Iyer
Download or read book A PATH TO DISCOVER written by Natesan Ramalingam Iyer. This book was released on 2020-06-27. Available in PDF, EPUB and Kindle. Book excerpt: This is the author’s second book. His first book, ‘Adventures in three worlds’ is a recollection of the events that happened in the author’s life and the lessons he learned. This book is like a treatise on the world’s reaction to the coronavirus, people are still going through. Life is just like a sea, we are moving constantly. Nothing stays with us, what remains are just the memories of some people who touched us like waves. We are loved when we are born; we may be loved or hated based on how we have managed ourselves in between. War and peace are part of life. The world produces war-mongers as well as great souls like Mahatma Gandhi, Albert Einstein, Abraham Lincoln, and Nelson Mandela. The virus brouhaha is an awakening to change. Now everyone know Wuhan! The book briefly covers aspects of globalization, history of pandemics, biological warfare, Hindu scriptures, Covid-19 and India's lessons to the world. By applying cognizance, sobriety, intelligence and wisdom we have been creating superb technology and management systems; yet we have missed Brahminical way of living. ‘A Path to Discover’ may open a debate with views and counter-views. In one sentence, what lessons have we learned from the virus? The great Hindu Saint Tulsidas gave the answer in 16th century: In ‘dependence’ there is no happiness, even in a dream.
