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Tacrolimus Ointment

2013-04-17 Medical
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Release : 2013-04-17
Genre : Medical
Kind : eBook
Book Rating : 099/5 ( reviews)

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Book Synopsis Tacrolimus Ointment by : T. Ruzicka

Download or read book Tacrolimus Ointment written by T. Ruzicka. This book was released on 2013-04-17. Available in PDF, EPUB and Kindle. Book excerpt: Therapeutic breakthroughs in medicine are usually accompanied by a wealth of data. Often they result in a change of disease treatment paradigms. Tacrolimus ointment is the first in the new class of steroid-free Topical Immunomodulators (TIMs), and as such represents the first true breakthrough since the introduction of topical steroids more than 50 years ago for the treatment of T-cell mediated inflammatory skin diseases such as atopic dermatitis. This book gives an easy-to-read overview of the discovery and the development of Tacrolimus ointment for the treatment of atopic dermatitis. Summarising the largest clinical trial program ever conducted in dermatology for a new treatment with more than 13000 patients, it offers a detailed insight into the efficacy and safety profile of Tacrolimus ointment. Based on this large body of data and extensive personal experience, the authors offer practical and hands-on guidance for the physician as to when and how to use Tacrolimus ointment in daily practice.

The Billion-Dollar Molecule

2013-08-20 Business & Economics
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Release : 2013-08-20
Genre : Business & Economics
Kind : eBook
Book Rating : 81X/5 ( reviews)

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Book Synopsis The Billion-Dollar Molecule by : Barry Werth

Download or read book The Billion-Dollar Molecule written by Barry Werth. This book was released on 2013-08-20. Available in PDF, EPUB and Kindle. Book excerpt: Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing—atom by atom—both a new life-saving immunosuppressant drug, and a drug to combat the virus that causes AIDS. You will be hooked from start to finish, as you go from the labs, where obsessive, fiercely competitive scientists struggle for a breakthrough, to Wall Street, where the wheeling and dealing takes on a life of its own, as Boger courts investors and finally decides to take Vertex public. Here is a fascinating no-holds-barred account of the business of science, which includes an updated epilogue about the most recent developments in the quest for a drug to cure AIDS.

First International Workshop on FK-506

1987
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Release : 1987
Genre :
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis First International Workshop on FK-506 by : International Workshop on FK 506 (1, 1987, Göteborg)

Download or read book First International Workshop on FK-506 written by International Workshop on FK 506 (1, 1987, Göteborg). This book was released on 1987. Available in PDF, EPUB and Kindle. Book excerpt:

Therapeutic Modulation of Cytokines

1996-01-23 Medical
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Release : 1996-01-23
Genre : Medical
Kind : eBook
Book Rating : 816/5 ( reviews)

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Book Synopsis Therapeutic Modulation of Cytokines by : M. W. Bodmer

Download or read book Therapeutic Modulation of Cytokines written by M. W. Bodmer. This book was released on 1996-01-23. Available in PDF, EPUB and Kindle. Book excerpt: Cytokines are peptide or protein cell-to-cell signaling molecules that play vital roles in normal cell and tissue homeostasis, as well as in responses to infectious agents. Because of their importance in virtually all forms of pathology, the pharmaceutical industry is devoting great effort to develop methods for the control of cytokine synthesis or action. This is the first volume to bring together experts from academia and the pharmaceutical industry to discuss problems and solutions in the therapeutic control of cytokines. An introductory section reviews the biology, physiology, and pathology of cytokines. Internationally recognized scientists then discuss the development of low molecular mass inhibitors, including inhibitors of cytokine convertases and oligonucleotide drugs. The potential use of natural inhibitors such as soluble receptors, interleukin-1 receptor antagonists, and anti-cytokine antibodies is detailed. This interesting book also covers intracellular signaling pathways induced by pro-inflammatory cytokines and the bio-modulatory activity of specific cytokines such as TGF-ß. Therapeutic Modulation of Cytokines will interest academic scientists in biochemistry, cell biology, pharmacology, and molecular biology and biological scientists in the pharmaceutical and biopharmaceutical industries.

ImmunoPharmaceuticals

1995-11-27 Medical
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Release : 1995-11-27
Genre : Medical
Kind : eBook
Book Rating : 885/5 ( reviews)

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Book Synopsis ImmunoPharmaceuticals by : Edward S. Kimball

Download or read book ImmunoPharmaceuticals written by Edward S. Kimball. This book was released on 1995-11-27. Available in PDF, EPUB and Kindle. Book excerpt: Written by a leading researcher in immunology, ImmunoPharmaceuticals specifically focuses on immunologically active drugs recently tested for clinical activity or recently approved for medical use. Each chapter focuses on a single drug or class of drugs and discusses data from basic and preclinical research concerning mechanisms of action. Preclinical models are compared with clinical findings to allow the reader to evaluate the predictive value of those models. Featured drugs are being studied for therapy of cancer, arthritic disease, autoimmune disease, immunodeficiency disease, transplantation, and determination of sepsis. Overviews of the retinoids in cancer therapy and preclinical studies on flavonoids are featured.

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