The Molecular and Cellular Basis for Parkinson's Disease

2019-10-14 Science

Author : Thomas Müller
Release : 2019-10-14
Genre : Science
Kind : eBook
Book Rating : 485/5 ( reviews)

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Book Synopsis The Molecular and Cellular Basis for Parkinson's Disease by : Thomas Müller

Download or read book The Molecular and Cellular Basis for Parkinson's Disease written by Thomas Müller. This book was released on 2019-10-14. Available in PDF, EPUB and Kindle. Book excerpt: The focus on dopamine-sensitive motor symptoms, in association with the improvement of motor complications in the heterogeneous disease entity Parkinson's disease, has led to a certain standstill in research.This Special Issue provides new concepts and new ideas on the pathogenesis, genetics, and clinical maintenance of Parkinson's disease and related disorders. Not only new experimental findings, but also clinical outcomes, case series, and research on alternative, non-pharmacological therapies are included.The objective is to bridge the currently increasing gap between experimental and clinical research on Parkinson's disease and related disorders.

The Molecular and Cellular Basis for Parkinson's Disease

2019 Electronic books

Author : Thomas Müller
Release : 2019
Genre : Electronic books
Kind : eBook
Book Rating : 492/5 ( reviews)

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Book Synopsis The Molecular and Cellular Basis for Parkinson's Disease by : Thomas Müller

Download or read book The Molecular and Cellular Basis for Parkinson's Disease written by Thomas Müller. This book was released on 2019. Available in PDF, EPUB and Kindle. Book excerpt: The focus on dopamine-sensitive motor symptoms, in association with the improvement of motor complications in the heterogeneous disease entity Parkinson's disease, has led to a certain standstill in research.false,This Special Issue provides new concepts and new ideas on the pathogenesis, genetics, and clinical maintenance of Parkinson's disease and related disorders. Not only new experimental findings, but also clinical outcomes, case series, and research on alternative, non-pharmacological therapies are included.false,The objective is to bridge the currently increasing gap between experimental and clinical research on Parkinson's disease and related disorders.

The Molecular and Cellular Basis of Neurodegenerative Diseases

2018-03-29 Medical

Author : Michael S. Wolfe
Release : 2018-03-29
Genre : Medical
Kind : eBook
Book Rating : 057/5 ( reviews)

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Book Synopsis The Molecular and Cellular Basis of Neurodegenerative Diseases by : Michael S. Wolfe

Download or read book The Molecular and Cellular Basis of Neurodegenerative Diseases written by Michael S. Wolfe. This book was released on 2018-03-29. Available in PDF, EPUB and Kindle. Book excerpt: The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics. Diseases are presented first, with common mechanisms later. Individual chapters discuss each major neurodegenerative disease, integrating this information to offer multiple molecular and cellular mechanisms that diseases may have in common. This book provides readers with a timely update on this rapidly advancing area of investigation, presenting an invaluable resource for researchers in the field. Covers the spectrum of neurodegenerative diseases and their complex genetic, pathological, biochemical and cellular features Focuses on leading hypotheses regarding the biochemical and cellular dysfunctions that cause neurodegeneration Details features, advantages and limitations of animal models, as well as prospects for therapeutic development Authored by internationally recognized leaders in the field Includes illustrations that help clarify and consolidate complex concepts

Parkinson's Disease: Cell Vulnerability and Disease Progression

2016-01-04 Neurosciences. Biological psychiatry. Neuropsychiatry

Author : Javier Blesa
Release : 2016-01-04
Genre : Neurosciences. Biological psychiatry. Neuropsychiatry
Kind : eBook
Book Rating : 763/5 ( reviews)

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Book Synopsis Parkinson's Disease: Cell Vulnerability and Disease Progression by : Javier Blesa

Download or read book Parkinson's Disease: Cell Vulnerability and Disease Progression written by Javier Blesa. This book was released on 2016-01-04. Available in PDF, EPUB and Kindle. Book excerpt: Download PDF Download EPUB Parkinson's disease is a neurodegenerative disorder that affects 1.5% of the global population over 65 years of age. The hallmark feature of this disease is the degeneration of dopamine neurons in the substantia nigra pars compacta and a consequent striatal dopamine deficiency. The pathogenesis of Parkinson's Disease remains unclear. Despite tremendous growth in recent years in our knowledge of the molecular basis of Parkinson's Disease and the molecular pathways of cell death important questions remain regarding why are substantia nigra cells especially vulnerable, which mechanisms underlie progressive cell loss or what do Lewy bodies or alpha-synuclein reveal about disease progression. Understanding the different vulnerability of the dopaminergic neurons from midbrain regions and the mechanisms whereby pathology becomes widespread are primary objectives of basic and clinical research in Parkinson's Disease. This e-Book discusses the etiopathogenesis of Parkinson's Disease, presenting a series of papers that provide up-to-date, state-of-the-art information on molecular and cellular mechanisms involved in the neurodegeneration process in the disease, the role of activation of functional anatomical organization of the basal ganglia and in particular habitual vs goal directed systems as a factor of neuronal vulnerability, the possibility that Parkinson's Disease coulb be a prion disease and how genetic factors linked to familial and sporadic forms of PD. We hope that this e-Book will stimulate the continuing efforts to understand the cell and physiological mechanisms underlying the origin of Parkinson's Disease.

Parkinson's Disease

2016-12-19 Medical

Author : Patrik Verstreken
Release : 2016-12-19
Genre : Medical
Kind : eBook
Book Rating : 055/5 ( reviews)

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Book Synopsis Parkinson's Disease by : Patrik Verstreken

Download or read book Parkinson's Disease written by Patrik Verstreken. This book was released on 2016-12-19. Available in PDF, EPUB and Kindle. Book excerpt: Parkinson’s Disease: Molecular Mechanisms Underlying Pathology explores the molecular pathways at the basis of the cellular defects connected to Parkinson’s disease, the second most common neurodegenerative disease, and the most common movement disorder. This book presents the latest research on the pathways and mechanisms that have been discovered to play a role in Parkinson's pathology. This focus on mechanisms rather than individual genes allows the contributors to elaborate on overlapping and joint functions of different causative genes. Readers will find descriptions of model systems that present parallels (and differences) between discoveries in different species, demonstrating the importance of multidisciplinary research that spans a broad array of technologies and model organisms. Written from both a cross-methodology and cross-species perspective, the book provides readers with the current state of knowledge on the molecular biology of Parkinson’s. Written by experts in the field that focus on pathways and mechanisms implicated in Parkinson’s pathology Draws parallels between multidisciplinary discoveries in different model organisms using an array of technologies Provides a cross-methodology and cross-species approach to understanding the molecular biology of Parkinson’s disease Includes approximately 25 color Illustrations and diagrams to explain concepts and models Focuses on key pathways and mechanisms (as opposed to model organism or gene) to provide a multidisciplinary approach to Parkinson’s disease

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