Share

Personalized Treatment of Breast Cancer

2016-05-24 Medical
Download Personalized Treatment of Breast Cancer PDF Online Free

Author :
Release : 2016-05-24
Genre : Medical
Kind : eBook
Book Rating : 528/5 ( reviews)

GET EBOOK


Book Synopsis Personalized Treatment of Breast Cancer by : Masakazu Toi

Download or read book Personalized Treatment of Breast Cancer written by Masakazu Toi. This book was released on 2016-05-24. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the essential factors in the personalization of treatment for primary breast cancer. These include host issues, lymph node surgery, radiation therapy, and preoperative systemic treatment requiring specialized knowledge, multidisciplinary care experience, techniques, and research. Locoregional treatment in conjunction with systemic treatments is another important factor, with options for local therapy significantly affected by genetic BRCA mutation. Axillary treatment issues have become top priorities in recent primary breast cancer care, and these are highlighted in the book’s presentation of technological advances in lymph node mapping and diagnosis, axillary clearance in patients with nodal metastasis, and the role of axillary surgery. Attention is also given to locoregional treatment after preoperative systemic therapy. Because therapeutic impact differs depending upon biological characteristics such as tumor subtype, local therapy should be based both on tumor biology and on therapeutic response in parallel. Associated translational research and mathematical prediction tools such as nomograms also are introduced. This book provides the essence of primary breast cancer care, particularly its individualization with novel therapeutic concepts and strategies, and will greatly benefit physicians and clinical investigators in breast cancer institutions.

Breast Cancer: From Bench to Personalized Medicine

2022-05-14 Medical
Download Breast Cancer: From Bench to Personalized Medicine PDF Online Free

Author :
Release : 2022-05-14
Genre : Medical
Kind : eBook
Book Rating : 97X/5 ( reviews)

GET EBOOK


Book Synopsis Breast Cancer: From Bench to Personalized Medicine by : Saima Shakil Malik

Download or read book Breast Cancer: From Bench to Personalized Medicine written by Saima Shakil Malik. This book was released on 2022-05-14. Available in PDF, EPUB and Kindle. Book excerpt: This book provides detailed information on the etiology, pathogenesis, diagnosis, prognosis, and treatment strategies for breast cancer. The first section of the book presents epidemiology, risk factors, histopathological, immunohistochemistry, and molecular subtypes of breast cancer based on the receptor status. It also discusses the association of breast cancer with other hormone-sensitive cancers. The second section of the book covers cover BRCA1 and BRCA2-associated breast carcinogenesis, early-stage progression of breast cancer, and noninvasive biomarkers for the early detection of breast cancer. It also discusses the role of epigenetic modifications and non-coding RNAs in breast cancer metastasis and explores these as the biomarkers and therapeutic targets for breast cancer therapy. Further, it discusses the role of fibrinolytic mechanisms and circulating tumor cells in breast cancer diagnosis, prognosis, and treatment. The book also provides an update on oral poly(ADP-ribose) polymerase (PARP) inhibitors to treat breast cancer. Finally, it offers potential new options for personalized therapies for breast cancer patients, including optimizing drug dosage and identifying genetic changes associated with cancer symptom occurrence and severity.

Economic Dimensions of Personalized and Precision Medicine

2019-04-22 Business & Economics
Download Economic Dimensions of Personalized and Precision Medicine PDF Online Free

Author :
Release : 2019-04-22
Genre : Business & Economics
Kind : eBook
Book Rating : 23X/5 ( reviews)

GET EBOOK


Book Synopsis Economic Dimensions of Personalized and Precision Medicine by : Ernst R. Berndt

Download or read book Economic Dimensions of Personalized and Precision Medicine written by Ernst R. Berndt. This book was released on 2019-04-22. Available in PDF, EPUB and Kindle. Book excerpt: Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement of PPM is a challenge in traditional clinical, reimbursement, and regulatory landscapes because it is costly to develop and introduces a wide range of scientific, clinical, ethical, and socioeconomic issues. PPM raises a multitude of economic issues, including how information on accurate diagnosis and treatment success will be disseminated and who will bear the cost; changes to physician training to incorporate genetics, probability and statistics, and economic considerations; questions about whether the benefits of PPM will be confined to developed countries or will diffuse to emerging economies with less developed health care systems; the effects of patient heterogeneity on cost-effectiveness analysis; and opportunities for PPM’s growth beyond treatment of acute illness, such as prevention and reversal of chronic conditions. This volume explores the intersection of the scientific, clinical, and economic factors affecting the development of PPM, including its effects on the drug pipeline, on reimbursement of PPM diagnostics and treatments, and on funding of the requisite underlying research; and it examines recent empirical applications of PPM.

Personalized Medicine in Oncology

2022
Download Personalized Medicine in Oncology PDF Online Free

Author :
Release : 2022
Genre :
Kind : eBook
Book Rating : 205/5 ( reviews)

GET EBOOK


Book Synopsis Personalized Medicine in Oncology by : Ari VanderWalde

Download or read book Personalized Medicine in Oncology written by Ari VanderWalde. This book was released on 2022. Available in PDF, EPUB and Kindle. Book excerpt: Nowhere is the explosion in comprehensive genomic testing more evident than in oncology. Multiple consensus guidelines now recommend molecular testing as the standard of care for most metastatic tumors. To aid in the advancement of this rapidly changing field, we intend this Special Issue of JPM to focus on technical developments in the genomic profiling of cancer, detail promising somatic alterations that either are, or have a high likelihood of being, relevant in the near future, and to address issues related to the pricing and value of these tests.The last few years have seen the cost of molecular testing decrease by orders of magnitude. In 2018, we saw the first “site-agnostic” drug approvals in cancer (for microsatellite unstable cancer (PD-1 inhibitors) and NTRK-fusions (TRK inhibitors)). Research on targetable mutations, determination of genetic “signatures” that can use multiple individual genes/pathways, development of targeted therapy, and insight into the value of new technology remains at the cutting edge of research in this field. We are soliciting papers that present new technologies to assess predictive biomarkers in cancer, original research (pre-clinical or clinical) that demonstrates promise for particular targeted therapies in cancer, and articles that explore the clinical and financial impacts of this paradigmatic shift in cancer diagnostics and treatment.

Bayesian Predictive Modeling for Personalized Treatment Selection for Breast Cancer Patients

2019 Breast
Download Bayesian Predictive Modeling for Personalized Treatment Selection for Breast Cancer Patients PDF Online Free

Author :
Release : 2019
Genre : Breast
Kind : eBook
Book Rating : /5 ( reviews)

GET EBOOK


Book Synopsis Bayesian Predictive Modeling for Personalized Treatment Selection for Breast Cancer Patients by : Md Monzur Murshed

Download or read book Bayesian Predictive Modeling for Personalized Treatment Selection for Breast Cancer Patients written by Md Monzur Murshed. This book was released on 2019. Available in PDF, EPUB and Kindle. Book excerpt:

You may also like...