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Introduction to Macromolecular Crystallography

2011-09-20 Science
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Release : 2011-09-20
Genre : Science
Kind : eBook
Book Rating : 638/5 ( reviews)

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Book Synopsis Introduction to Macromolecular Crystallography by : Alexander McPherson

Download or read book Introduction to Macromolecular Crystallography written by Alexander McPherson. This book was released on 2011-09-20. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and approachable introduction to crystallography — now updated in a valuable new edition The Second Edition of this well-received book continues to offer the most concise, authoritative, and easy-to-follow introduction to the field of crystallography. Dedicated to providing a complete, basic presentation of the subject that does not assume a background in physics or math, the book's content flows logically from basic principles to methods, such as those for solving phase problems, interpretation of Patterson maps and the difference Fourier method, the fundamental theory of diffraction and the properties of crystals, and applications in determining macromolecular structure. This new edition includes a vast amount of carefully updated materials, as well as two completely new chapters on recording and compiling X-ray data and growing crystals of proteins and other macromolecules. Richly illustrated throughout to clarify difficult concepts, this book takes a non-technical approach to crystallography that is ideal for professionals and graduate students in structural biology, biophysics, biochemistry, and molecular biology who are studying the subject for the first time.

Macromolecular Crystallography

2007-08-23 Language Arts & Disciplines
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Release : 2007-08-23
Genre : Language Arts & Disciplines
Kind : eBook
Book Rating : 972/5 ( reviews)

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Book Synopsis Macromolecular Crystallography by : Mark R. Sanderson

Download or read book Macromolecular Crystallography written by Mark R. Sanderson. This book was released on 2007-08-23. Available in PDF, EPUB and Kindle. Book excerpt: Macromolecular crystallography is the study of macromolecules using X-ray crystallographic techniques to determine their molecular structure. This title synthesises contributions from a team of internationally recognized leaders, offering chapters on conventional and high-throughput methods.

Macromolecular Crystallography

1997 Computer simulation
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Release : 1997
Genre : Computer simulation
Kind : eBook
Book Rating : 779/5 ( reviews)

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Book Synopsis Macromolecular Crystallography by : Charles W. Carter

Download or read book Macromolecular Crystallography written by Charles W. Carter. This book was released on 1997. Available in PDF, EPUB and Kindle. Book excerpt: Annotation Accurate molecular structures is vital for rational drug design and for structure based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding. * Phases * Map interpretation and refinement * Analysis and software.

Macromolecular Crystallography

2011-12-01 Science
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Release : 2011-12-01
Genre : Science
Kind : eBook
Book Rating : 302/5 ( reviews)

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Book Synopsis Macromolecular Crystallography by : Maria Armenia Carrondo

Download or read book Macromolecular Crystallography written by Maria Armenia Carrondo. This book was released on 2011-12-01. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a collection of the contributions presented at the 42nd Erice Crystallographic Course whose main objective was to train the younger generation on advanced methods and techniques for examining structural and dynamic aspects of biological macromolecules. The papers review the techniques used to study protein assemblies and their dynamics, including X-ray diffraction and scattering, electron cryo-electron microscopy, electro nanospray mass spectrometry, NMR, protein docking and molecular dynamics. A key theme throughout the book is the dependence of modern structural science on multiple experimental and computational techniques, and it is the development of these techniques and their integration that will take us forward in the future.

Protein Crystallography

2008-04-28 Science
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Release : 2008-04-28
Genre : Science
Kind : eBook
Book Rating : 843/5 ( reviews)

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Book Synopsis Protein Crystallography by : Eaton E. Lattman

Download or read book Protein Crystallography written by Eaton E. Lattman. This book was released on 2008-04-28. Available in PDF, EPUB and Kindle. Book excerpt: The proteome remains a mysterious realm. Researchers have determined the structures of only a small fraction of the proteins encoded by the human genome. Crystallography continues to be the primary method used to determine the structures of the remaining unknown proteins. This imaging technique uses the diffraction of X-rays to determine a protein’s three-dimensional molecular structure. Drawing on years of research and teaching experience, Eaton E. Lattman and Patrick J. Loll use clear examples and abundant illustrations to provide a concise and accessible primer on protein crystallography. Discussing the basics of diffraction, the behavior of two- and three-dimensional crystals, phase determination (including MIR and MAD phasing and molecular replacement), the Patterson function, and refinement, Lattman and Loll provide a complete overview of this important technique, illuminated by physical insights. The crisp writing style and simple illustrations will provide beginner crystallographers with a guide to the process of unraveling protein structure.

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