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Author : Emma Raven
Release : 2015-10-27
Genre : Science
Kind : eBook
Book Rating : 110/5 ( reviews)
Book Synopsis Heme Peroxidases by : Emma Raven
Download or read book Heme Peroxidases written by Emma Raven. This book was released on 2015-10-27. Available in PDF, EPUB and Kindle. Book excerpt: This book will provide an up to date handbook that is unique in its combination of both the general aspects of heme protein structure and the function in a single volume.
Author : Clare Hawkins
Release : 2021-10-08
Genre : Medical
Kind : eBook
Book Rating : 635/5 ( reviews)
Book Synopsis Mammalian Heme Peroxidases by : Clare Hawkins
Download or read book Mammalian Heme Peroxidases written by Clare Hawkins. This book was released on 2021-10-08. Available in PDF, EPUB and Kindle. Book excerpt: Mammalian heme peroxidase enzymes play a critical role in innate immune responses and disease prevention. The formation of potent chemical oxidants is essential to this protective physiologic activity in immunity. Although highly beneficial in the context of immune defense, it is now well established that peroxidases and their overproduction of oxidants contribute to the initiation and persistence of many chronic inflammatory conditions in the cardiovascular, neurologic, respiratory, renal, and gastrointestinal systems. Peroxidasins, a protein family related to heme peroxidases, play a novel role in tissue biogenesis and matrix assembly, which are also attracting attention in different pathological contexts. Given the diverse roles of mammalian heme peroxidases and the breadth and incidence of pathologies associated with these enzymes, there has been significant interest in modulating peroxidase activity as a therapeutic strategy. This book highlights recent developments in our understanding of the chemistry, biochemistry and biological roles of mammalian peroxidases and their associated oxidants, their involvement in both innate immunity and chronic inflammatory disease in a variety of end organs, and potential therapeutic approaches to modulate and prevent damaging reactions. Key Features Structure and biosynthesis of mammalian peroxidases Reactivity of hypohalous acids with biological substrates Peroxidases in innate immunity Peroxidases in human pathology Modulation of peroxidase-induced biological damage
Author : H. Brian Dunford
Release : 1999
Genre : Peroxidase
Kind : eBook
Book Rating : /5 ( reviews)
Book Synopsis Heme Peroxidases by : H. Brian Dunford
Download or read book Heme Peroxidases written by H. Brian Dunford. This book was released on 1999. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Eduardo Torres
Release : 2010-08-20
Genre : Science
Kind : eBook
Book Rating : 278/5 ( reviews)
Book Synopsis Biocatalysis Based on Heme Peroxidases by : Eduardo Torres
Download or read book Biocatalysis Based on Heme Peroxidases written by Eduardo Torres. This book was released on 2010-08-20. Available in PDF, EPUB and Kindle. Book excerpt: The last systematic description of heme peroxidases was published in 1999 by Brian Dunford, from the University of Alberta in Canada. The book Heme per- idases covers discussion on three-dimensional structure, reaction mechanism, kinetics, and spectral properties of representative enzymes from bacterial, plant, fungal, and animal origin. Since 1999, vast information on basic but also applied aspects of heme peroxidases has been generated. We believe fusion of these two aspects will bene?t research of those dedicated to development of biocatalytic process. The aim of this book is to present recent advances on basic aspects such as evolution, structure–function relation, and catalytic mechanism, as well as applied aspects, such as bioreactor and protein engineering, in order to provide the tools for rational design of enhanced biocatalysts and biocatalytic processes. The book does not include an exhaustive listing of references but rather a selected collection to enrich discussion and to allow envisioning future directions for research. This book is organized in three parts. In Part I, current knowledge of structure and mechanism of peroxidases is covered. From the molecular phylogeny, going through the in?uence of structural factors over oxidative ability to the molecular mechanism of catalysis, the authors intend to provide an understanding of per- idases at the molecular level. The understanding of the fundamental behavior of peroxidases will allow further adequation, design, and/or optimization of pero- dase-based catalysis to a particular process. In Part II, research on potential applications of peroxidases in several ?elds is presented and discussed.
Author : George Georgiou
Release : 1991
Genre : SCIENCE
Kind : eBook
Book Rating : /5 ( reviews)
Book Synopsis Protein Refolding by : George Georgiou
Download or read book Protein Refolding written by George Georgiou. This book was released on 1991. Available in PDF, EPUB and Kindle. Book excerpt: the refolding process is often the critical bottleneck in the production of high-value proteins, and recently acquired insights have yet to be translated into technological advantages. These proceedings bridge the gap between fundamental and applied studies, addressing such issues as in vivo protein folding, protein aggregation and inclusion body formation, elucidation of the folding pathway, characterization of folding intermediates, and practical considerations in protein renaturation. The symposium was part of the 199th ACS National Meeting, Boston, April 1990. Annotation copyrighted by Book News, Inc., Portland, OR
