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Chronic Myeloproliferative Disorders

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Release : 2008-08-27
Genre : Medical
Kind : eBook
Book Rating : 989/5 ( reviews)

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Book Synopsis Chronic Myeloproliferative Disorders by : Tariq Mughal

Download or read book Chronic Myeloproliferative Disorders written by Tariq Mughal. This book was released on 2008-08-27. Available in PDF, EPUB and Kindle. Book excerpt: With the new classification of chronic myeloproliferative disorders, and the rise of interest in molecularly targeted therapies, this timely text brings together international experts on the topic to discuss the current technologies and their implications for the treatment of patients. This title comprehensively covers chronic myeloid leukemia and Ph-negative chronic myeloproliferative disorders and is an essential resource for all practitioners in Hematologic Oncology.

Myeloproliferative Neoplasms

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Release : 2012-02-03
Genre : Medical
Kind : eBook
Book Rating : 884/5 ( reviews)

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Book Synopsis Myeloproliferative Neoplasms by : Tiziano Barbui

Download or read book Myeloproliferative Neoplasms written by Tiziano Barbui. This book was released on 2012-02-03. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on three of the main categories of myeloproliferative neoplasm: polycythemia vera, essential thrombocythemia, and primary myelofibrosis. Relevant laboratory and clinical advances are comprehensively covered, and great emphasis is placed on the practical issues that challenge physicians in their daily practice. The main topics considered thus include contemporary diagnostic approaches, the value and limitations of mutation screening for diagnostic and prognostic purposes, risk stratification in terms of both survival and other disease complications such as leukemic transformation and thrombosis, and modern therapeutic strategies, including conventional drugs, allogeneic stem cell transplantation, and experimental drugs still under study. The reader will find Critical Concepts and Management Recommendations in Myeloproliferative Neoplasms to be an invaluable and up-to-date source of information from leading authorities in the field.

Molecular Basis of Chronic Myeloproliferative Disorders

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Release : 2012-12-06
Genre : Medical
Kind : eBook
Book Rating : 382/5 ( reviews)

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Book Synopsis Molecular Basis of Chronic Myeloproliferative Disorders by : H.L. Pahl

Download or read book Molecular Basis of Chronic Myeloproliferative Disorders written by H.L. Pahl. This book was released on 2012-12-06. Available in PDF, EPUB and Kindle. Book excerpt: Since the first description of Philadelphia chromosome-negative chronic myeloproliferative disorders more than 100 years ago, the diagnosis and therapy of these conditions have been based primarily on clinical experience and judgement. Until recently very little was known about the molecular basis of these diseases. In order to spark research in this area basic scientists and clinicians from various parts of the world have contributed to this volume, the first of its kind to put together the current knowledge. The book deals with the new WHO classification of these disorders, novel aspects of diagnostic pathology, the search for disease-relevant genes utilizing molecular biology and proteomic techniques, the description of the roles of PVR-1 and VHL genes for polycythemias and the discovery of the gene mutation responsible for the idiopathic hypereosinophilic syndrome. A chapter on anagrelide, an important novel drug for the treatment of primary thrombocythemia, is included.

Fast Facts: Myeloproliferative Neoplasms

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Release : 2019-02-11
Genre : Medical
Kind : eBook
Book Rating : 804/5 ( reviews)

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Book Synopsis Fast Facts: Myeloproliferative Neoplasms by : R.A. Mesa

Download or read book Fast Facts: Myeloproliferative Neoplasms written by R.A. Mesa. This book was released on 2019-02-11. Available in PDF, EPUB and Kindle. Book excerpt: Presentation of the myeloproliferative neoplasms (MPNs) varies widely, and correct diagnosis and management can be challenging, and is becoming more complex as understanding of the underlying molecular basis for these disorders emerges. Appropriate management is increasingly informed by accurate risk stratification founded on understanding of cytogenetic and molecular markers, as well as the clinical presentation. 'Fast Facts: myeloproliferative neoplasms' focuses on the three most common chronic MPNs: • Essential thrombocythemia (ET) – characterized by increased platelet count • Polycythemia vera (PV) – characterized by excessive production of red blood cells • Primary myelofibrosis – a more severe and heterogenous disorder that may overlap with ET and PV but is commonly associated with anemia. Written by two leading experts in the field, Fast Facts: myeloproliferative neoplasms provides concise, up-to-date and practical guidance on the accurate diagnosis, risk stratification and management of these MPNs. It also provides key insights into our growing understanding of the underlying molecular and genetic basis of these disorders, and how this is informing risk stratification and management strategies. This concise handbook will be invaluable to clinicians, medical students, nurses, pharmacists and scientists in understanding and overcoming the everyday and rarer challenges associated with MPN.

Managing Myeloproliferative Neoplasms

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Release : 2016-03-31
Genre : Medical
Kind : eBook
Book Rating : 775/5 ( reviews)

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Book Synopsis Managing Myeloproliferative Neoplasms by : Ruben A. Mesa

Download or read book Managing Myeloproliferative Neoplasms written by Ruben A. Mesa. This book was released on 2016-03-31. Available in PDF, EPUB and Kindle. Book excerpt: This is a concise, practical, case-based book documenting examples and scenarios that will help you manage challenging clinical issues for patients with myeloproliferative neoplasms. The editors and authors have strived to distil the very latest information in this rapidly advancing field in a way that will help you to update your practice and manage your patients. The key focuses are: diagnosis, both standard and challenging; both day-to-day management as well as special situations such as surgery, thrombotic events and pregnancy; and finally, managing evolving situations with MPN such as progression to acute myeloid leukemia. This book is an outstanding resource that includes a discussion of both classical myeloproliferative neoplasms, such as essential thrombocythemia, polycythemia vera and myelofibrosis, and also less common disorders such as systemic mast cell disease, hypereosinophilia, MPN/MBS overlap syndromes and atypical CML, amongst others. This book is a practical reference for practitioners, hematologists, medical oncologists and trainees.

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