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Alzheimer's Disease: Biology, Biophysics And Computational Models

2022-01-06 Medical
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Release : 2022-01-06
Genre : Medical
Kind : eBook
Book Rating : 130/5 ( reviews)

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Book Synopsis Alzheimer's Disease: Biology, Biophysics And Computational Models by : Don Kulasiri

Download or read book Alzheimer's Disease: Biology, Biophysics And Computational Models written by Don Kulasiri. This book was released on 2022-01-06. Available in PDF, EPUB and Kindle. Book excerpt: Alzheimer's disease (AD) is the leading cause of dementia and, unfortunately, remains incurable. The social, emotional and financial implications of AD are immeasurable, and about 47 million people worldwide are affected by AD or other forms of dementia. As lifespans are improved by healthcare systems worldwide, age-associated neurodegenerative diseases are imposing an increasing challenge to science. It is becoming imperative for us to understand the causes of these diseases, AD in particular, at molecular and cellular levels. Starting with the broader picture from a biological perspective, this book takes the reader through fascinating dynamics within and outside of neurons in the brain.Alzheimer's Disease: Biology, Biophysics and Computational Models helps the reader to understand AD from mechanistic and biochemical perspectives at intra- and inter-cellular levels. It focuses on biochemical pathways and modeling associated with AD. Some of the recent research on biophysics and computational models related to AD are explained using context-driven computational and mathematical modeling and essential biology is discussed to understand the modeling research.

Computational Modeling of Drugs Against Alzheimer’s Disease

2023-06-30 Medical
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Release : 2023-06-30
Genre : Medical
Kind : eBook
Book Rating : 112/5 ( reviews)

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Book Synopsis Computational Modeling of Drugs Against Alzheimer’s Disease by : Kunal Roy

Download or read book Computational Modeling of Drugs Against Alzheimer’s Disease written by Kunal Roy. This book was released on 2023-06-30. Available in PDF, EPUB and Kindle. Book excerpt: This second edition volume expands on the previous edition with updated descriptions on different computational methods encompassing ligand-based, structure-based, and combined approaches with their recent applications in anti-Alzheimer drug design. Different background topics like recent advancements in research on the development of novel therapies and their implications in the treatment of Alzheimer’s Disease (AD) have also been covered for completeness. Special topics like basic information science methods for insight into neurodegenerative pathogenesis, drug repositioning and network pharmacology, and online tools to predict ADMET behavior with reference to anti-Alzheimer drug development have also been included. In the Neuromethods series style, chapter include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, Computational Modeling of Drugs Against Alzheimer’s Disease, Second Edition is a valuable resource for all researchers and scientists interested in learning more about this important and developing field.

Computational Systems Biology Of Synaptic Plasticity: Modelling Of Biochemical Pathways Related To Memory Formation And Impairement

2017-06-09 Science
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Release : 2017-06-09
Genre : Science
Kind : eBook
Book Rating : 398/5 ( reviews)

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Book Synopsis Computational Systems Biology Of Synaptic Plasticity: Modelling Of Biochemical Pathways Related To Memory Formation And Impairement by : Don Kulasiri

Download or read book Computational Systems Biology Of Synaptic Plasticity: Modelling Of Biochemical Pathways Related To Memory Formation And Impairement written by Don Kulasiri. This book was released on 2017-06-09. Available in PDF, EPUB and Kindle. Book excerpt: This book demonstrates the power of mathematical thinking in understanding the biological complexity that exists within the brain. It looks at the latest research on modelling of biochemical pathways within synapses, and provides a clear background for the study of mathematical models related to systems biology. Discussion then focusses on developments in computational models based on networks linked to synaptic plasticity. The models are used to understand memory formation and impairment and they provide a mathematical basis for memory research.Computational Systems Biology of Synaptic Plasticity is a valuable source of knowledge to postgraduate students and researchers in computational systems biology, and as a reference book for various techniques that are needed in modelling biological processes.

Computational Neurogenetic Modeling

2010-05-05 Technology & Engineering
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Release : 2010-05-05
Genre : Technology & Engineering
Kind : eBook
Book Rating : 551/5 ( reviews)

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Book Synopsis Computational Neurogenetic Modeling by : Lubica Benuskova

Download or read book Computational Neurogenetic Modeling written by Lubica Benuskova. This book was released on 2010-05-05. Available in PDF, EPUB and Kindle. Book excerpt: This is a student text, introducing the scope and problems of a new scientific discipline - Computational Neurogenetic Modeling (CNGM). CNGM is concerned with the study and development of dynamic neuronal models for modeling brain functions with respect to genes and dynamic interactions between genes. These include neural network models and their integration with gene network models. This new area brings together knowledge from various scientific disciplines.

Computational and Experimental Studies in Alzheimer's Disease

2024-03-29 Science
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Release : 2024-03-29
Genre : Science
Kind : eBook
Book Rating : 345/5 ( reviews)

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Book Synopsis Computational and Experimental Studies in Alzheimer's Disease by : Kunal Bhattacharya

Download or read book Computational and Experimental Studies in Alzheimer's Disease written by Kunal Bhattacharya. This book was released on 2024-03-29. Available in PDF, EPUB and Kindle. Book excerpt: This reference book compiles the recent advances in computational and experimental modelling to screen and manage Alzheimer’s disease. It covers basic etiopathology and various in vitro and in vivo strategies of disease intervention. The book discusses how computer-aided drug design approaches reduce costs and increase biological test efficiency. It reviews the screening for anti-Alzheimer drugs and biomarker analysis of disease inhibitors. The book also explores mechanistic aspects of neurodegeneration and the use of natural products as therapeutics for Alzheimer’s disease. Key features: Elaborates on the computational modelling of protein target inhibitors as anti-Alzheimer’s agents Explains the role of phytomolecules and natural products in Alzheimer’s therapy Reviews preclinical ways to assess drugs focusing on Alzheimer’s disease Covers biomarker analysis for Alzheimer’s disease Discusses the onset and progression of Alzheimer’s disease The book is meant for professionals, researchers, and students of neuroscience, psychology, and computational neurosciences.

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