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Advances in Diagnosis and Therapy of Neuroendocrine Neoplasms

2021-01-29 Medical
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Release : 2021-01-29
Genre : Medical
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Book Rating : 453/5 ( reviews)

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Book Synopsis Advances in Diagnosis and Therapy of Neuroendocrine Neoplasms by : Eva Segelov

Download or read book Advances in Diagnosis and Therapy of Neuroendocrine Neoplasms written by Eva Segelov. This book was released on 2021-01-29. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue is dedicated to neuroendocrine neoplasms (NENs), a category of malignancy that demonstrates wide clinical heterogeneity, posing major challenges in diagnosis and management. There have been significant advances in the field of NEN genomics, pathology, imaging, and treatment over the past five years. NENs are examples of rare tumours (although their incidence and prevalence are increasing) where international collaborative efforts have allowed the generation of high-level evidence to guide optimal patient-centred care. This issue presents both reviews and original papers to provide comprehensive state-of-the-art understanding of this fascinating disease.

Advances in Diagnosis and Therapy of Neuroendocrine Neoplasms

2021
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Release : 2021
Genre :
Kind : eBook
Book Rating : 467/5 ( reviews)

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Book Synopsis Advances in Diagnosis and Therapy of Neuroendocrine Neoplasms by : Eva Segelov

Download or read book Advances in Diagnosis and Therapy of Neuroendocrine Neoplasms written by Eva Segelov. This book was released on 2021. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue is dedicated to neuroendocrine neoplasms (NENs), a category of malignancy that demonstrates wide clinical heterogeneity, posing major challenges in diagnosis and management. There have been significant advances in the field of NEN genomics, pathology, imaging, and treatment over the past five years. NENs are examples of rare tumours (although their incidence and prevalence are increasing) where international collaborative efforts have allowed the generation of high-level evidence to guide optimal patient-centred care. This issue presents both reviews and original papers to provide comprehensive state-of-the-art understanding of this fascinating disease.

The Spectrum of Neuroendocrine Neoplasia

2020-10-19 Medical
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Release : 2020-10-19
Genre : Medical
Kind : eBook
Book Rating : 919/5 ( reviews)

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Book Synopsis The Spectrum of Neuroendocrine Neoplasia by : Sylvia L. Asa

Download or read book The Spectrum of Neuroendocrine Neoplasia written by Sylvia L. Asa. This book was released on 2020-10-19. Available in PDF, EPUB and Kindle. Book excerpt: Neuroendocrine neoplasms comprise a large family of proliferative lesions that involve almost every part of the body. Our understanding of their cells of origin as well as the pathology, pathophysiology and genetics of these neoplasms has made tremendous advances in the last few decades. While they are often discussed as separate entities in textbooks of gastroenteropancreatic pathology and pulmonary pathology, their scope is much broader. The book conveys the similarities and differences of these fascinating tumors that may be found from the hypothalamus and pituitary to the rectum, and in soft tissue as well as in many organs. Written by experts in the field, the authors emphasize their structural, functional, predictive and prognostic features and attempt to provide the clinical context that allows improved diagnosis and therapy while building on the genetics that clarifies patterns of inheritance and predisposition to tumor development through precursor lesions. The Spectrum of Neuroendocrine Neoplasia provides a broad overview of neuroendocrine neoplasms using a practical approach to diagnosis, histological classification and therapy, and presents the most important and significant developments of the technologies used to diagnose, classify and treat them.

Neuroendocrine Neoplasia Management

2021-07-16 Medical
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Release : 2021-07-16
Genre : Medical
Kind : eBook
Book Rating : 307/5 ( reviews)

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Book Synopsis Neuroendocrine Neoplasia Management by : Giordano Beretta

Download or read book Neuroendocrine Neoplasia Management written by Giordano Beretta. This book was released on 2021-07-16. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the most recent update on the management of neuroendocrine neoplasia (NEN), a term covering all tumors of various organs and/or with a particular histology, including MEN (multiple endocrine neoplasia) related tumors, MiNEN (mixed neuroendocrine-non-neuroendocrine neoplasms), NEC (neuroendocrine carcinoma) and Merkel’s carcinoma. NENs are heterogeneous in their biology, clinical presentation and prognosis, showing a great variability in aggressiveness and therapy response. As a result, their treatment is based on a large spectrum of options. The standard therapies are surgery in early disease, various loco-regional procedures in certain conditions and mostly of a palliative nature in metastatic disease. At present, thanks to our increased understanding of molecular signaling pathways, several pharmacological approaches can be used in patients with advanced NENs. Somatostatin analogs display both anti-tumor effects and symptom control. Novel peptide-radio-receptor treatment (PRRT) is used in patients with well differentiated tumors. The agents targeting angiogenesis and/or PI3K/AKT/mTOR pathway, alone or in combination with analogues, have provided encouraging results in advanced disease. The first part of the book focuses on the history, epidemiology and the most relevant scientific achievements, covering the discoveries in genetic and molecular biology, the endoscopic techniques with guided biopsy, and the metabolic imaging with hybrid PET/CT and MRI/CT. It particularly highlights the emerging strategies in therapy, surgery and mini-invasive surgery as well as loco-regional and systemic treatments, including targeted therapy and/or biological therapies. The second part then explores the management of NENs of various anatomical origins and/or with peculiar biology. It describes the range of the current options and the most relevant results from the clinical trials. This informative book provides valuable insights for all those interested in the management of neuroendocrine neoplasia.

Neuroendocrine Tumors: Review of Pathology, Molecular and Therapeutic Advances

2016-08-31 Medical
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Release : 2016-08-31
Genre : Medical
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Book Rating : 260/5 ( reviews)

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Book Synopsis Neuroendocrine Tumors: Review of Pathology, Molecular and Therapeutic Advances by : Aejaz Nasir

Download or read book Neuroendocrine Tumors: Review of Pathology, Molecular and Therapeutic Advances written by Aejaz Nasir. This book was released on 2016-08-31. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive subspecialty reference book on NeuroEndocrine Tumor (NET) pathology brings together the diagnostic and clinical expertise of an outstanding team of practicing neuroendocrine pathologists and oncologists. In addition to in-depth coverage of clinico-pathologic aspects of NETs of the various organ systems, the recent histological grading and staging schemes proposed by the North American and European NeuroEndocrine Tumor Societies (NANETS, ENETS), the World Health Organization (WHO) and the American Joint Committee on Cancer (AJCC), this book also focuses on the recent molecular and therapeutic advances in the field of NET pathology and oncology. Neuroendocrine Tumors: Review of Pathology, Molecular and Therapeutic Advances will be an essential reference book for anatomic pathology (histopathology) residents, fellows, surgical pathologists, researchers, oncologists, surgeons and other medical professionals practicing advanced NET Pathology and Oncology in academia, community, private practice and research settings.

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