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Acute Symptomatic Seizures and Epileptiform Abnormalities: Management and Outcomes

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Release : 2023-04-26
Genre : Science
Kind : eBook
Book Rating : 592/5 ( reviews)

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Book Synopsis Acute Symptomatic Seizures and Epileptiform Abnormalities: Management and Outcomes by : Vineet Punia

Download or read book Acute Symptomatic Seizures and Epileptiform Abnormalities: Management and Outcomes written by Vineet Punia. This book was released on 2023-04-26. Available in PDF, EPUB and Kindle. Book excerpt:

Prognosis and Management of Acute Symptomatic Seizures: a Prospective, Multicenter, Observational Study

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Release : 2023
Genre :
Kind : eBook
Book Rating : /5 ( reviews)

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Book Synopsis Prognosis and Management of Acute Symptomatic Seizures: a Prospective, Multicenter, Observational Study by : Julia Herzig-Nichtweiß

Download or read book Prognosis and Management of Acute Symptomatic Seizures: a Prospective, Multicenter, Observational Study written by Julia Herzig-Nichtweiß. This book was released on 2023. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Background Acute symptomatic epileptic seizures are frequently seen in neurocritical care. To prevent subsequent unprovoked seizures, long-term treatments with antiseizure medications are often initiated although supporting evidence is lacking. This study aimed at prospectively assessing the risk of unprovoked seizure relapse with respect to the use of antiseizure medications. It was hypothesized that after a first acute symptomatic seizure of structural etiology, the cumulative 12-month risk of unprovoked seizure relapse is ≤ 25%. Methods Inclusion criteria were age ≥ 18 and acute symptomatic first-ever epileptic seizure; patients with status epilepticus were excluded. Using telephone and mail interviews, participants were followed for 12 months after the acute symptomatic first seizure. Primary endpoint was the occurrence and timing of a first unprovoked seizure relapse. In addition, neuro-intensivists in Germany were interviewed about their antiseizure treatment strategies through an anonymous online survey. Results Eleven of 122 participants with structural etiology had an unprovoked seizure relapse, resulting in a cumulative 12-month risk of 10.7% (95%CI, 4.7%-16.7%). None of 19 participants with a non-structural etiology had a subsequent unprovoked seizure. Compared to structural etiology alone, combined infectious and structural etiology was independently associated with unprovoked seizure relapse (OR 11.1; 95%CI, 1.8-69.7). Median duration of antiseizure treatment was 3.4 months (IQR 0-9.3). Seven out of 11 participants had their unprovoked seizure relapse while taking antiseizure medication; longer treatment durations were not associated with decreased risk of unprovoked seizure relapse. Following the non-representative online survey, most neuro-intensivists consider 3 months or less of antiseizure medication to be adequate. Conclusions Even in case of structural etiology, acute symptomatic seizures bear a low risk of subsequent unprovoked seizures. There is still no evidence favoring long-term treatments with antiseizure medications. Hence, individual constellations with an increased risk of unprovoked seizure relapse should be identified, such as central nervous system infections causing structural brain damage. However, in the absence of high-risk features, antiseizure medications should be discontinued early to avoid overtreatment

Epilepsy

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Release : 2021-08-02
Genre : Medical
Kind : eBook
Book Rating : 824/5 ( reviews)

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Book Synopsis Epilepsy by : Gregory D. Cascino

Download or read book Epilepsy written by Gregory D. Cascino. This book was released on 2021-08-02. Available in PDF, EPUB and Kindle. Book excerpt: Designed to provide a comprehensive but accessible introduction to epilepsy and seizure disorders, Epilepsy, 2nd edition provides state-of-the-art information in a concise format useful to a wide audience, from neurology residents to epilepsy fellows and practitioners. This illustrated guide to the assessment, diagnosis, and treatment of epilepsy is a valuable resource enabling clinicians to stay on top of the latest recommendations for best practice.

Atlas of Epilepsies

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Release : 2010-09-20
Genre : Medical
Kind : eBook
Book Rating : 271/5 ( reviews)

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Book Synopsis Atlas of Epilepsies by : S.R. Benbadis

Download or read book Atlas of Epilepsies written by S.R. Benbadis. This book was released on 2010-09-20. Available in PDF, EPUB and Kindle. Book excerpt: Atlas of Epilepsies is a landmark, all-encompassing, illustrated reference work and hands-on guide to the diagnosis, management and treatment of epilepsy in all its forms and across all age groups. The premier text in the field with over one thousand images, the Atlas’s highly illustrative approach tackles the difficult subject of epileptic seizures and epileptic syndromes, accompanied by sequential photographs of each management step. Intraoperative photographs are accompanied by detailed figure legends describing nuances, subtleties, and the thought processes involved in each step, providing a fuller understanding of each procedure. The Atlas draws on the expertise of over 300 internationally-renowned experts, and is liberally interspersed with clinical insights and personal vignettes that offer helpful tips, technical advice and critical knowledge to the clinician and scholar. The thorough and complete table of contents includes dedicated sections or chapters on important topics such as neonatal and pediatric seizures; imitators of epilepsy; EEG and neuroimaging; psychiatric and quality of life aspects of epilepsy; and a complete guide to treatment options including current and up-to-date chapters on pharmaceuticals, surgical procedures, and additional and alternative treatments. No other publication addresses epilepsies as thoroughly and completely as the Atlas of Epilepsies. Exhaustive and illustrative, convenient and current, this reference is sure to be the premier text on epilepsy for many years to come.

Neurohospitalist Medicine

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Release : 2011-09-29
Genre : Medical
Kind : eBook
Book Rating : 828/5 ( reviews)

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Book Synopsis Neurohospitalist Medicine by : S. Andrew Josephson

Download or read book Neurohospitalist Medicine written by S. Andrew Josephson. This book was released on 2011-09-29. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, the hospitalist model has become a dominant system for the delivery of inpatient care. Forces such as national mandates to improve safety and quality, and intense pressure to safely reduce length of hospital stays, are now exerting pressure on neurologists. To meet these challenges, a new neurohospitalist model is emerging. This is the first authoritative text to detail the advances and strategies for treating neurologic disease in a hospital setting. It includes chapters on specific acute neurologic diseases including stroke, epilepsy, neuromuscular disease and traumatic brain injury and also addresses common reasons for neurologic consultation in the hospital including encephalopathy, electrolyte disturbances and neurologic complications of pregnancy. Ethical and structural issues commonly encountered in neurologic inpatients are also addressed. This will be a key resource for any clinician or trainee caring for neurologic patients in the hospital including practising neurologists, internists and trainees across multiple subspecialities.

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